Newly designed ligands for a catalytic reaction to synthesize drugs and useful compounds

(GIST(Gwangju Institute of Science and Technology)) In a new study, scientists at Gwangju Institute of Science and Technology developed novel ligand molecules, which facilitate a catalytic reaction that generates useful compounds called chromanones. Chromanones, which have a stereocenter at C2 position (such as gonytolides C and lachnone C), are prominent structural motifs in natural products and possess numerous bioactivities. The newly synthesized ligand molecules offer an effective strategy f...